![]() ![]() The values of D* and f were higher in tumour progression patients than that in pseudoprogression patients ( p < 0.05). The values of ADC, D, DDC, and α values were lower in tumour progression patients than that in pseudoprogression patients ( p < 0.05). ![]() Interclass correlation coefficient (ICC) was used to evaluate the consistency of measurements. Receiver operating characteristic curves (ROC) analysis was used to investigate the diagnostic performance of different DWI parameters. ![]() The apparent diffusion coefficient (ADC) from a monoexponential model, the true diffusion coefficient (D), pseudodiffusion coefficient (D*) and perfusion fraction (f) from a biexponential model, and the distributed diffusion coefficient (DDC) and intravoxel heterogeneity index (α) from a stretched-exponential model were compared between tumour progression and pseudoprogression groups. All patients underwent conventional and multi-b diffusion-weighted MRI. Methodsįorty patients with pathologically confirmed glioblastoma exhibiting enhancing lesions after completion of chemoradiation therapy were enrolled in the study, which were then classified as tumour progression and pseudoprogression. To investigate the diagnostic performance of parameters derived from monoexponential, biexponential, and stretched-exponential diffusion-weighted imaging models in differentiating tumour progression from pseudoprogression in glioblastoma patients. ![]()
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